Cello Therapeutics, Inc. is a rapidly growing biotech company located in the Sorrento Valley—one of the major biotech hubs in the nation. Cello focuses on the development of novel nanotherapeutics based on biomimetic cell membrane-coated nanoparticles for cancer treatment. Cello offers a highly motivational and rewarding working environment with attractive salary and benefits.
Current Openings
Product Development Scientist
Responsibilities include:
- Capable of performing laboratory activities ranging from pre-formulation, formulation, process characterization, analytical testing, technology transfer and scale-up in an effective, and safe manner.
- Research, prototype, implement and scale up processes and chemistries for encapsulating varieties of drugs into nanoparticles.
- Supports qualification/validation & testing to support preclinical development and clinical development programs.
- Assist in development of manufacturing methods, processes work instructions, and SOPs for the production of biomimetic nanoparticle product lines.
- Determine requirements for equipment, tooling, materials, and methods of manufacturing, along with the ability to make continuous improvements to existing pipelines.
- Assist in preparation of technology transfer package and technology transfer.
- Assist in evaluating suppliers for raw materials, contract testing laboratories, and contract manufacturing organization.
- Regularly report work status and prepare written reports on work performed.
- Cooperatively working with personnel in other departments/collaborators: Formulation and Process Development, Quality Assurance and Regulatory Affairs, and collaborating partners.
Analytical Scientist/QC Specialist
Responsibilities include:
- Work on analytical method development and qualification/validation & testing to support preclinical development and clinical development programs.
- Develop analytical methods and assays for cell membranes, nanoparticles, cell membrane-coated nanoparticles, drug-loaded cell membrane-coated nanoparticles, and small molecules, carry out phase-appropriate qualification/validations for these methods, perform characterization testing, and troubleshooting experiments, and author corresponding documents.
- Establish cGMP compliant QC lab which includes evaluating and purchasing analytical instruments, setting up processes for analytical testing and release of raw materials, in-process materials and final drug substance and drug products.
- Evaluate the manufacturing process and manufacturing process technology transfer.
- Evaluate suppliers for raw materials, contract testing laboratories, and contract manufacturing organizations.
- Develop analytical methods and assays in biological fluids and prepare documentation for method transfer.
- Regularly report work status and prepare written reports on work performed.
- Cooperatively work with personnel in other departments, i.e. Formulation and Process Development, Quality Assurance and Regulatory Affairs, and collaborating partners.